Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
触目惊心,我国石家庄一家药企“上榜”,生产的无效头孢在非洲致儿童死亡,中文版里不知能否保留
评分##阔怕 保命请认准大厂原研药 以及第三世界真实从头惨到脚
评分##做了心理建设还是很难相信这种肮脏勾当是广泛存在的,FDA的形式主义和无所作为也是视人命如草芥
评分触目惊心,我国石家庄一家药企“上榜”,生产的无效头孢在非洲致儿童死亡,中文版里不知能否保留
评分##问题本身并不仅限于药企,本质上是policymaker和lawmaker如何能改良现有框架适应全球化,要不然迟早是下一个罗马。
评分##bad blood, billion dollar whale... fraud seems everywhere and beyond my wild imagination... one whistle blower against the world.. how many of us are brave enough to do this? luckily sometimes one would be sufficient
评分##阔怕 保命请认准大厂原研药 以及第三世界真实从头惨到脚
评分##读了三分之二终究还是决定放弃了????一个理科生只想看是啥原理导致仿制药的巨大问题,却不太想知道中间那么多复杂而又牵扯巨多的故事细节????????????然鹅这本书连uplcms都要解释一下但没解释清楚。。。
评分##这本书给我感觉和bad blood很像,也是一个记者多方访谈追踪揭露制药厂的骗局,读下来触目惊心,一遍遍问这是真的吗?真的吗?怎么会这样?FDA完全不可信了?简单结论就是千万不要再吃generic drugs了!
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